Anti-staphylococcal properties of four plant extracts against sensitive and multi-resistant bacterial strains isolated from cattle and rabbits

Medina, Mayra Fernanda Echeverría and Alaba, Peter Adeniyi and Estrada-Zuñiga, María Elena and Velázquez-Ordoñez, Valente and Barbabosa-Pliego, Alberto and Salem, Abdelfattah Z.M. and Alonso-Fresán, María Uxúa and Camacho-Díaz, Luis Miguel and Salem, Abdelfattah Z.M. (2017) Anti-staphylococcal properties of four plant extracts against sensitive and multi-resistant bacterial strains isolated from cattle and rabbits. Microbial Pathogenesis, 113. pp. 286-294.

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Abstract

The aim of this study is to investigate the biopotency of methanolic extracts of Vitex mollis, Psidium guajava, Dalbergia retusa, and Crescential alata leaves against various staphylococcal strains isolated from cattle and rabbits. Methicillin-resistant S. aureus strains were isolated from cattle, while other strains were isolated from rabbits using standard methodology. The total phytochemical phenolic and saponins contents were obtained being the main groups of the antinutritional factors. The antimicrobial activity of the extracts against the standard culture of S. aureus (control) and S. aureus isolated from cattle and rabbits were investigated comparatively relative to that of oxacillin. It was found that both the control S. aureus and the isolated S. aureus are susceptible to all the four plant extracts, and sensitive to oxacillin. Of all the S. aureus including the control, MRSA2 is the most susceptible to all the extracts at 1000 μg/mL, except that of V. mollis where it is the least susceptible. Among all the plant extracts, P. guajava is the most active against MRSA2 and SOSA2. Therefore, the isolates from cattle (MRSA1 and MRSA2) are more susceptible to all the plant extracts than the isolates from rabbits. Among all the rabbit isolates, CoNS3 is the least susceptible to the extracts. Since all the plant extracts exhibit remarkable inhibitory activities against all the S. aureus strains, they are promising towards the production of therapeutic drugs.

Item Type:	Article
Uncontrolled Keywords:	Antimicrobial agents Cattle Plant extracts Staphylococcus aureus Rabbits
Subjects:	S Agriculture > SB Plant culture S Agriculture > SF Animal culture T Technology > TP Chemical technology
Divisions:	Faculty of Engineering, Science and Mathematics > School of Engineering Sciences
Depositing User:	Mrs Patricia Nwokealisi
Date Deposited:	17 Aug 2018 11:45
Last Modified:	17 Aug 2018 11:45
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/11378

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