Genomic Interventions in Medicine

Aworunse, Oluwadurotimi S. and Adeniji, Oluwatomiwa and Oyesola, Olusola L. and Isewon, Itunuoluwa and Oyelade, O. J. and Obembe, Olawole O. (2018) Genomic Interventions in Medicine. Bioinformatics and Biology Insights, 12. pp. 1-12.

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Abstract

Lately, the term “genomics” has become ubiquitous in many scientific articles. It is a rapidly growing aspect of the biomedical sciences that studies the genome. The human genome contains a torrent of information that gives clues about human origin, evolution, biological function, and diseases. In a bid to demystify the workings of the genome, the Human Genome Project (HGP) was initiated in 1990, with the chief goal of sequencing the approximately 3 billion nucleotide base pairs of the human DNA. Since its completion in 2003, the HGP has opened new avenues for the application of genomics in clinical practice. This review attempts to overview some milestone discoveries that paved way for the initiation of the HGP, remarkable revelations from the HGP, and how genomics is influencing a paradigm shift in routine clinical practice. It further highlights the challenges facing the implementation of genomic medicine, particularly in Africa. Possible solutions are also discussed.

Item Type:	Article
Uncontrolled Keywords:	Genomics, Human Genome Project, pharmacogenomics, personalized medicine, gene therapy, diagnosis
Subjects:	Q Science > QA Mathematics > QA75 Electronic computers. Computer science Q Science > QH Natural history > QH301 Biology R Medicine > R Medicine (General)
Divisions:	Faculty of Engineering, Science and Mathematics > School of Electronics and Computer Science Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mrs Patricia Nwokealisi
Date Deposited:	11 Mar 2019 14:50
Last Modified:	11 Mar 2019 14:50
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/12477

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