Edobor-Osoh, A. and Ita, Benedict Iserom and Ajanaku, K. O. and Presa, P. de la and Ehi-Eromosele, C. O. and Olorunsola, S. J. and OWOLABI, Fisayo E. (2019) Synthesis, morphological, optical properties of functionalized La0.33Ca0.67MnO3 for antibacterial therapy. In: 13th Joint Conference on Chemistry (13th JCC), 2019, Online.
![[img]](http://eprints.covenantuniversity.edu.ng/style/images/fileicons/other.png) |
PDF
Download (906Kb) |
Abstract
A functionalized paramagnetic manganite La0.33Ca0.67MnO3 was investigated for its morphological, optical and antimicrobial properties. The manganite was capped by using a citrate ligand. The UV-visible spectrophotometer was used in monitoring the optical bands of the metal-citrate complex. It was observed to absorb in the visible region. The metal-citrate was reacted with a biologically active ligand (N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The optical bands observed from the metal-citrate were used in monitoring the reaction between the metal-citrate and N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The morphological property of the product formed was determined using SEMEDAX. The effect of the complex formed on the organic ligand, N-(3-nitrophenyl)-3-phenyl-2- (phenylsulfonamido) propanamide) was determined using 1H and 13C NMR. The bacterial inhibitory property of the metal-citrate- N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) complex was determined against Pseudomonas aeruginosa and Staphylococcus auerus. It was observed to inhibit the growth of Staphylococcus aureus only. The biological activities of the metal-citrate N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) suggest its use as an alternative antibacterial therapy.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Uncontrolled Keywords: | Pseudomonas aeruginosa, Staphylococcus aureus, Functionalization, Manganite and Nanoparticles |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Chemistry |
| Depositing User: | Mrs Patricia Nwokealisi |
| Date Deposited: | 29 Nov 2019 13:34 |
| Last Modified: | 29 Nov 2019 13:34 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/13008 |
Actions (login required)
 |
View Item |
