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Synthesis, morphological, optical properties of functionalized La0.33Ca0.67MnO3 for antibacterial therapy

Edobor-Osoh, A. and Ita, Benedict Iserom and Ajanaku, K. O. and Presa, P. de la and Ehi-Eromosele, C. O. and Olorunsola, S. J. and OWOLABI, Fisayo E. (2019) Synthesis, morphological, optical properties of functionalized La0.33Ca0.67MnO3 for antibacterial therapy. In: 13th Joint Conference on Chemistry (13th JCC), 2019, Online.

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A functionalized paramagnetic manganite La0.33Ca0.67MnO3 was investigated for its morphological, optical and antimicrobial properties. The manganite was capped by using a citrate ligand. The UV-visible spectrophotometer was used in monitoring the optical bands of the metal-citrate complex. It was observed to absorb in the visible region. The metal-citrate was reacted with a biologically active ligand (N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The optical bands observed from the metal-citrate were used in monitoring the reaction between the metal-citrate and N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The morphological property of the product formed was determined using SEMEDAX. The effect of the complex formed on the organic ligand, N-(3-nitrophenyl)-3-phenyl-2- (phenylsulfonamido) propanamide) was determined using 1H and 13C NMR. The bacterial inhibitory property of the metal-citrate- N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) complex was determined against Pseudomonas aeruginosa and Staphylococcus auerus. It was observed to inhibit the growth of Staphylococcus aureus only. The biological activities of the metal-citrate N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) suggest its use as an alternative antibacterial therapy.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Pseudomonas aeruginosa, Staphylococcus aureus, Functionalization, Manganite and Nanoparticles
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Engineering, Science and Mathematics > School of Chemistry
Depositing User: Mrs Patricia Nwokealisi
Date Deposited: 29 Nov 2019 13:34
Last Modified: 29 Nov 2019 13:34

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