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Nanochitosan derived from marine bacteria

Ahuekwe, Eze Frank and Isibor, Patrick Omoregie and Oziegbe, Olubukola and Salami, Abimbola Oluwadarasimi and Akinyosoye, Abimbola D. and Akinhanmi, Fadekemi and Oyewale, J. O. and Taiwo, Olugbenga S. and Akinwunmi, Ruth A. and Ajiboye, Ibukun and Adekeye, B. Temitope and Akinpelu, Sharon O. and Kuye, Alice O. and Bello, Oluwakemi A. and GEORGE, DANGO ZILPAH and Ojo-Omoniyi, Olusola A. and Popoola, Taiwo S. and Akinyemi, Oluwatobi D. and Adebayo, Glory P. and Oniha, M. I. and Iheagwam, Franklyn N and ADELODUN, COMFORT ADEBUKOLA and Orukotan, Kesioluwa E. and BILEWU, OLAYEMI FUNMILAYO and Onibokun, E. A. and FASUYI, NIFEMI OLAMIDE and Akinduti, P. A. and ONUSELOGU, CHINEDU CHARLES and Oshamika, Oyewumi O. and Oyesola, Olusola L. and Tersagh, Ichor d. and Ezekiel, O. M. and Nwinyi, Obinna and Ayanda and Akinnola, Olayemi O. and Oranusi, S. U. and Eni, A. O. and Popoola, J.O and Omonhinmin, Conrad A. and Olasehinde, G. I and Obembe, Olawole O. (2023) Nanochitosan derived from marine bacteria. In: Applications in Animal Husbandry, Aquaculture and Food Conservation. Next Generation Nanochitosan, pp. 147-168.

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Nanochitosans are polysaccharides produced by the alkalescent deacetylation of chitin and comprise a series of 2‐deoxy‐2 (acetylamino) glucose linked by ß‐(1‐4) glycosidic linkages. These are naturally formed from the deacetylation of shellfish shells and the exoskeleton of aquatic arthropods and crustaceans. Reports of chitosan production from unicellular marine bacteria inhabiting the sea, and possessing distinct animal‐ and plant‐like characteristics abound. This capacity to synthesize chitosan from chitin arises from response to stress under extreme environmental conditions, as a means of survival. Consequently, the microencapsulation of these nanocarriers results in new and improved chitosan nanoparticles, nanochitosan. This nontoxic bioactive material which can serve as an antibacterial agent, gene delivery vector as well as carrier for protein and drug release as compared with chitosan, is limited by its nonspecific molecular weight and higher composition of deacetylated chitin. This chapter highlights the biology and diversity of nanochitosan‐producing marine bacteria, including the factors influencing their activities, survival, and distribution. More so, the applications of marine bacterial nanochitosans in transfection and gene delivery; wound healing and drug delivery; feed supplement development and antimicrobial activity are discussed.

Item Type: Book Section
Uncontrolled Keywords: Chitosan Drug delivery Gene delivery Marine bacteria Nanochitosan Transfection
Subjects: Q Science > QH Natural history
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: nwokealisi
Date Deposited: 24 Apr 2023 22:39
Last Modified: 26 Apr 2023 12:39

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