Ncapayi, Vuyelwa and Ninan, Neethu and Thabang, C. Lebepe and Parani, Sundararajan and Girija, Aswathy Ravindran and Bright, Richard and Maluleke, Rodney and Aladesuyi, O. and Kodama, Tetsuya and Vasilev, Krasimir and Oluwafemi, Oluwatobi S. (2023) Photostable fluorescent Near-infrared colloidal Mn-doped CuInSe/ZnS quantum dots for cancer-bacteria dual imaging. Journal of Luminescence, 258.
![[img]](http://eprints.covenantuniversity.edu.ng/style/images/fileicons/application_pdf.png) |
PDF
Download (214kB) |
Abstract
Near-infrared quantum dots (NIR QDs) with tunable fluorescence emission are promising materials for bioimaging applications. However, they face several challenges, including low photostability, reduced brightness, and poor fluorescence emission. Herein, we report the synthesis of NIR emitting colloidal Mn-doped CuInSe/ZnS QDs synthesised via the hydrothermal method in a commercial pressure cooker. These fluorescent materials had a peak corresponding to photoluminescence maxima at 765 nm and had good photostability. The in vitro analysis showed that the assynthesised QDs displayed good cell viability against mouse colon carcinoma (C26) cells. They selectively screened Gram-positive bacteria from Gram-negative bacteria and effectively targeted prostate cancer cells compared to normal cells. Thus, they can be used for cancer-bacteria dual-imaging in the biomedical field.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Chemistry |
| Depositing User: | ORIGBOEYEGHA |
| Date Deposited: | 31 Jul 2024 12:37 |
| Last Modified: | 31 Jul 2024 12:37 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/18335 |
Actions (login required)
 |
View Item |
