Evaluation of antibacterial activity of Pisidium guajava and Gongronema Latifolium

Nwinyi, O. C. and Chinedu, S. N. and Ajani, O. O. (2008) Evaluation of antibacterial activity of Pisidium guajava and Gongronema Latifolium. Journal of Medicinal Plants Research, 2 (8). pp. 189-192. ISSN ISSN 1996-0875

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Abstract

Pisidium guajava and Gongronema latifolium are local plants used traditionally in south-eastern Nigeria to treat ailments such as cough, loss of appetite, malaria and stomach disorders. In this study, aqueous and ethanolic leaf extracts of P. guajava and G. latifolium were screened for antibacterial activity against two clinically isolated organisms of the gastrointestinal tract, Escherichia coli and Staphylococcus aureus. Results obtained show that leaf extracts of both plants possess significant antibacterial activities against the two isolates. Ethanolic extracts showed more inhibitory effect compared to the aqueous extracts. Extracts of P. guajava exhibited higher inhibitory effect than that of G. latifolium. The diameter of zones of inhibition by the leaf extracts of P. guajava was 8 - 16 mm and 14 - 21 mm respectively for the aqueous and ethanolic extracts. The minimum inhibitory concentrations (MICs) were 5.0 and 0.625 mg ml-1 respectively for the aqueous and ethanolic extracts of P. guajava. For the extracts of G. latifolium, the diameter of zones of inhibition was between 6 and 10 mm while MICs were 10.0 and 2.5 mg ml-1 respectively for the aqueous and ethanolic extracts

Item Type:	Article
Uncontrolled Keywords:	Pisidium guajava, Gongronema latifolium, antibacterial activity, minimum inhibitory concentration (MIC), Escherichia coli, Staphylococcus aureus
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Engineering, Science and Mathematics > School of Chemistry
Depositing User:	Mr Olayinka O. AJANI
Date Deposited:	05 Dec 2013 09:53
Last Modified:	05 Dec 2013 09:53
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/1936

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