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A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation

Sowunmi, Akintunde and Akinrinola, Ibukun A. and Gbotosho, Grace O. and Okuboyejo, Titilope M and Happi, Christian T. (2012) A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation. SOURCE Journal of Tropical Pediatrics, 58. p. 263.

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Abstract

A dose regimen of artesunate and amodiaquine based on arm span- or age range (DRAAAS), derived from a study of 1674 children, was compared with standard dose regimen of the same drugs calculated according to body weight (SDRAA) in 68 malarious children. Children on DRAAAS received 0.8–1.0 of artesunate/kg and 0.9–1.2 times amodiaquine/kg compared with those receiving SDRAA. Parasite and fever clearance and fall in hematocrit in the first 3 days were similar; both regimens were well tolerated. DRAAAS is simple and is efficacious.

Item Type: Article
Uncontrolled Keywords: Dose regimen arm span anti- malarial Children
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Mrs Patricia Nwokealisi
Date Deposited: 08 Oct 2014 14:58
Last Modified: 08 Oct 2014 14:58
URI: http://eprints.covenantuniversity.edu.ng/id/eprint/2816

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