Impact of antibiotic prophylaxis on wound infection after cesarean section in a situation of expected higher risk

Mah, W. Manuel and Pyper, Alyson and Oni, Gbolahan Impact of antibiotic prophylaxis on wound infection after cesarean section in a situation of expected higher risk. American Journal of Infection Control.

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Abstract

Background: To measure rates of incisional surgical site infection (ISSI) after cesarean section (CS) and to assess risks for infection. Methods: Prospective surveillance for ISSI at a 540-bed hospital in Saudi Arabia by using Centers for Disease Control and Prevention definitions for infection and the National Nosocomial Infections Surveillance (NNIS) system risk index. Results: Seven hundred thirty-five CSs were studied from September 1998 to July 1999; 72% were emergency procedures, despite a 95% rate of antenatal care. The overall ISSI rate was 2.8% (95% confidence interval [CI], 1.7%-4.3%). The rate for NNIS risk category 0 was 2.4% (95% CI, 1.3%-4.2%; n = 536) and for category 1 was 4.1% (95% CI, 1.8%-8.6%; n = 170). In the multivariate analysis, the only independent risks for ISSI were duration of surgery (OR = 1.01; 95% CI, 1.00-1.03; P =.02) and no antibiotic prophylaxis (OR = 3.09; 95% CI, 1.10-9.11; P =.04). Antibiotic prophylaxis was inconsistently administered among both emergency and elective CS. Infection control procedures were inadequate in the obstetric suite operating room. Conclusions: Despite deficient infection control practices in the setting described, ISSI rates after CS were judged “acceptable” compared with NNIS benchmark rates. This was attributed to prescribing antibiotic prophylaxis for patients at low risk as well as high risk of infection. (AJIC Am J Infect Control 2001;29:85-8)

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RB Pathology
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User:	Professor Gbolahan Oni
Date Deposited:	03 Apr 2015 22:08
Last Modified:	03 Apr 2015 22:08
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/4558

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