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Theoretical Investigation and Computation of Time Dependent CW NMR Blood-flow Signal for the Estimation of Blood Flow Parameters

Odoh, E. O. and De, Dilip Kumar (2009) Theoretical Investigation and Computation of Time Dependent CW NMR Blood-flow Signal for the Estimation of Blood Flow Parameters. African Physical Review, 3. pp. 65-75.

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Abstract

A new approach is described here for Continuous Wave Nuclear Magnetic Resonance (CW NMR) application to quantification of blood flow in human blood vessels. To study the time dependence of the flow signal generated by the flowing blood spins, a simple model of CW NMR excitation scheme is used for an accurate estimation of blood steady velocity, V0, the peak pusatile velocity, 0 VPulse and the blood vessel cross-section. Starting with the time dependent Bloch equations, we have generated an equation that presents a CW NMR blood signal, whose profile corresponds to the human cardiac cycle. Using a spin-spin relaxation time of 0.1 s, blood steady velocity of 20 cm/s (typical of a healthy human) and a peak pulse velocity of 30 cm/s, our model provides results very close to those obtained by conventional NMR pulse machines and other modality like the Ultrasound Doppler (US) technique. The application of our CW NMR model technique for the determination of blood flow parameters of importance covers a wide range of variations seen in human patients.

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QC Physics
Divisions: Faculty of Engineering, Science and Mathematics > School of Physics
Depositing User: Mrs Hannah Akinwumi
Date Deposited: 12 Apr 2015 19:24
Last Modified: 12 Apr 2015 20:04
URI: http://eprints.covenantuniversity.edu.ng/id/eprint/4888

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