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Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

Ajani, Olayinka O. (2014) Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine. European Journal of Medicinal Chemistry, 85. pp. 688-715. ISSN 0223-5234

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Abstract

Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are complementary in shapes and charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be relatively easy to administer either as intramuscular solutions, oral capsules or rectal suppositories. This work deals with recent advances in the synthesis and pharmacological diversities of quinoxaline motifs which might pave ways for novel drugs development.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Engineering, Science and Mathematics > School of Chemistry
Depositing User: Mr Olayinka O. AJANI
Date Deposited: 15 Apr 2015 08:10
Last Modified: 15 Apr 2015 08:10
URI: http://eprints.covenantuniversity.edu.ng/id/eprint/4928

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