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Effects of Solanum aethiopicum Fruit on Plasma Lipid Profile in rats

Chinedu, S. N. and Eboji, Okwuchukwu K. and Rotimi, S. O (2013) Effects of Solanum aethiopicum Fruit on Plasma Lipid Profile in rats. Advances in Bioresearch, 4 (4). pp. 79-84. ISSN 0976-4585; Online ISSN 2277-1573

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To investigate the effects of the inclusion of graded levels of S. aethiopicum fruit in the feed of rats on plasma lipid profile. 20 male and 20 female rats were grouped into four groups of 5rats each per sex and fed on diets containing 0%, 4%, 8% and 12% S. aethiopicum fruit for 28days. Thereafter, the plasma triacylglycerol, cholesterol, HDL cholesterol, VLDL cholesterol and LDL cholesterol were estimated. Atherogenic and coronary indexes were also calculated. The diets resulted in a significant (p<0.05) reduction in plasma cholesterol, triacylglycerol, LDL cholesterol and VLDL cholesterol. A significant (p<0.05) increase in HDL cholesterol was also observed. The fruit also caused a significant (p<0.05) reduction in atherogenic and coronary risk indexed with female rats having better reduction. This work demonstrated the ability of S. aethiopicum fruit to improved the lipid profile of the plasma thereby lowering the risk of cardiovascular diseases

Item Type: Article
Uncontrolled Keywords: Solanum aethiopicum, Lipid profile, Atherogenic index, Coronary risk index
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Mrs Patricia Nwokealisi
Date Deposited: 27 Nov 2015 10:20
Last Modified: 15 Aug 2016 15:49

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