Nwinyi, Obinna and Chinedu, S. N. and Ajani, O. O.
Evaluation of antibacterial activity of Pisidium guajava
and Gongronema Latifolium.
Journal of Medical Plants Research, 2 (8).
Pisidium guajava and Gongronema latifolium are local plants used traditionally in south-eastern Nigeria
to treat ailments such as cough, loss of appetite, malaria and stomach disorders. In this study, aqueous
and ethanolic leaf extracts of P. guajava and G. latifolium were screened for antibacterial activity
against two clinically isolated organisms of the gastrointestinal tract, Escherichia coli and
Staphylococcus aureus. Results obtained show that leaf extracts of both plants possess significant
antibacterial activities against the two isolates. Ethanolic extracts showed more inhibitory effect
compared to the aqueous extracts. Extracts of P. guajava exhibited higher inhibitory effect than that of
G. latifolium. The diameter of zones of inhibition by the leaf extracts of P. guajava was 8 - 16 mm and 14
- 21 mm respectively for the aqueous and ethanolic extracts. The minimum inhibitory concentrations
(MICs) were 5.0 and 0.625 mg ml-1 respectively for the aqueous and ethanolic extracts of P. guajava. For
the extracts of G. latifolium, the diameter of zones of inhibition was between 6 and 10 mm while MICs
were 10.0 and 2.5 mg ml-1 respectively for the aqueous and ethanolic extracts.
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