Abstract:
The expensive and technology limited setting of CD4 count
testing is a major setback to the initiation of HAART in a resource limited
country like Nigeria. Simple and inexpensive tools such as Hemoglobin (Hb) measurement
and Total Lymphocyte Count (TLC) are recommended as substitute marker. In order
to assess the correlations of these parameters with CD4 count, 100 “apparently
healthy” male volunteers tested HIV positive aged ≥20 years but ≤40
years were recruited and from whom Hb, Hct, TLC and CD4 count were obtained.
The correlation coefficients, R, the Nash-Sutcliffe Coefficient of Efficiency
(CoE) and the p-values of the ANOVA model of Hb, Hct and TLC with CD4 count
were assessed. The assessments show that there is no significant relationship
of any of these parameters with CD4 count and the correlation coefficients are
very weak. This study shows that Hb, Hct and TLC cannot be substitute for CD4
count as this might lead to certain individuals’ deprivation of required
treatment.
Charles Iheanyichi Emuchay, Shemaiah Olufemi Okeniyi and Joshua Olusegun Okeniyi, 2014. Correlation Between Total Lymphocyte Count, Hemoglobin, Hematocrit and CD4 Count in HIV Patients in Nigeria. Pakistan Journal of Biological Sciences, 17: 570-573.
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