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A new norlignan from Taxodium ascendens

Zhang, Yu-Mei and Tan, Ning-Hua and Zeng, Guang-Zhi and Adebayo, H. A. and JI, Chang-Jiu (2009) A new norlignan from Taxodium ascendens. ScienceDirect. pp. 361-363.

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Abstract

A new norlignan, (2R,3R,4S,5S)-2,4-bis(4-hydroxyphenyl)-3,5-dihydroxy-tetrahydropyran (1), together with 9 known compounds were isolated from the branches and leaves of Taxodium ascendens. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidences. Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC50 value of 4.27 μg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC50 values of 2.12 and 3.71 μg/ml, respectively. ©

Item Type: Article
Uncontrolled Keywords: Taxodiaceae Taxodium ascendens Norlignan
Subjects: Q Science > QH Natural history
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Mrs Patricia Nwokealisi
Date Deposited: 16 Mar 2017 09:41
Last Modified: 16 Mar 2017 09:41
URI: http://eprints.covenantuniversity.edu.ng/id/eprint/7942

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