<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Anti-inflammatory and antioxidant activities of fractions and compound\r\nfrom Ricinodendron heudelotii (Baill.)"^^ . "Medicinal plants have been documented over the years to play vital role in promoting human health. The study\r\nevaluated the anti-inflammatory and anti-oxidant activities of different fractions and isolated compound from\r\nRicinodendron heudelotii leaves. The leaves of Ricinodendron heudelotii were extracted with ethanol and further\r\npartitioned sequentially using petroleum ether, ethylacetate and butanol. Bioassay–guided fractionation of the\r\nethylacetate fraction was done using repeated column chromatographic technique while the structural elucidation\r\nof pure compound was carried out using mass spectra, 13C and 1H NMR analyses. Antioxidant potential of the\r\nfractions and isolated compound were evaluated with 2,2-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid)\r\n(ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays and anti-inflammatory effect of\r\nfractions was measured by their inhibitory potency on nitric oxide (NO).\r\nCorilagin, an amorphous tannin was isolated and structurally elucidated. Corilagin showed scavenging effect\r\nagainst ABTS and DPPH radicals which vary in a dose dependent manner. It also showed an antioxidant potential\r\nwith IC50 value of 0.003 mg/mL comparable to vitamin C 0.001 mg/mL) used as standard. The butanol and\r\nethylacetate fractions exhibited significant (p < 0.05) NO inhibition of 60 and 69% respectively after treatment of\r\nRAW 264.7 macrophages with lipopolysaccharide. These results demonstrated the role of isolated corilagin as a\r\npromising potent antioxidant while the ethylacetate and butanol fractions suppressed the expression of an\r\ninflammation mediator by inhibiting nitric oxide."^^ . "2019" . . . "Elsevier"^^ . . . "Heliyon"^^ . . . . . . . . . . . . . . . . . . . . . . . "H. A."^^ . "Adebayo"^^ . "H. A. Adebayo"^^ . . "Ying-Jun"^^ . "Zhang"^^ . "Ying-Jun Zhang"^^ . . "Isaacson"^^ . "Adelani"^^ . "Isaacson Adelani"^^ . . "E. E. J."^^ . "Iweala"^^ . "E. E. J. Iweala"^^ . . "TEMITOPE ARIKE"^^ . "ISHOLA"^^ . "TEMITOPE ARIKE ISHOLA"^^ . . "Omolara Faith"^^ . "Yakubu"^^ . "Omolara Faith Yakubu"^^ . . . . . . "Anti-inflammatory and antioxidant activities of fractions and compound\r\nfrom Ricinodendron heudelotii (Baill.) (PDF)"^^ . . . "1-s2.0-S2405844019364394-main.pdf"^^ . . . "Anti-inflammatory and antioxidant activities of fractions and compound\r\nfrom Ricinodendron heudelotii (Baill.) (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #13183 \n\nAnti-inflammatory and antioxidant activities of fractions and compound \nfrom Ricinodendron heudelotii (Baill.)\n\n" . "text/html" . . . "QH301 Biology"@en . . . . . . . . . . . . . . . . . . . . . "H. A."^^ . "Adebayo"^^ . "H. A. Adebayo"^^ . ""^^ . . "Omolara Faith"^^ . "Yakubu"^^ . "Omolara Faith Yakubu"^^ . ""^^ . . "TEMITOPE ARIKE"^^ . "ISHOLA"^^ . "TEMITOPE ARIKE ISHOLA"^^ . ""^^ . . "Isaacson"^^ . "Adelani"^^ . "Isaacson Adelani"^^ . ""^^ . . "Ying-Jun"^^ . "Zhang"^^ . "Ying-Jun Zhang"^^ . ""^^ . . "E. E. J."^^ . "Iweala"^^ . "E. E. J. Iweala"^^ . ""^^ .