%D 2007
%K Resistant, plasmids, Proteus, diabetic, wounds.
%N 15
%V 6
%J African Journal of Biotechnology
%T Widespread plasmid resistance genes among Proteus
species in diabetic wounds of patients in the Ahmadu
Bello university teaching hospital (ABUTH) Zaria
%P 1757-1762
%I Academic Journals
%A S. C Yah
%A N. O Eghafona
%A S. U. Oranusi
%A A. M. Abouo
%L eprints3986
%X Plasmids have been known to play a major role in the dissemination of antibiotics resistance genes in a
microbial population. In this background, 148 Proteus species comprising of 97 Proteus mirabilis and
51 Proteus vulgaris were isolated from diabetic wounds. Seventy-six strains had varied multi-drug
resistance (MDR) pattern encoded on transferable plasmid gene with a very high frequency (2 x10-4 to 4
x 10-2 per donor cell) by conjugation. 34% of the strains lost the antibiotic resistance plasmids marker
after sodium dodecyl sulfate (SDS) mediated curing. The rest of the plasmid markers were non
transferable. The results indicated that plasmids carry varied dissemination of antibiotics resistance
markers to distant recipient cells, indicating clonal transfer among bacterial strains.