<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Haematopoietic induction and hepatic protective roles\r\nof Hepacare® in CCl4-induced hepatic damaged rats"^^ . "Herbal formulations are plant parts used as raw materials\r\nfor self-administered pharmaceutical remedies, and\r\nmany of them are being sold without any scientific validation\r\nfor their potency and efficacy. This research work was aimed at\r\nevaluating the haematopoietic, biochemical, and histologi- cal\r\neffects of Hepacare®, a popularly sold herbal formulation in\r\nNigeria against carbon tetrachloride (CCl4)-mediated liver damage\r\nin rats. Haematological analysis showed significant reduction\r\n(p < 0.05) in haemoglobin, red blood cell, packed cell\r\nvolume, and platelet counts in CCl4-treated group when compared\r\nwith the untreated group. These parameters were however\r\nreversed across the groups treated with the herbal formulation.\r\nLevels of alkaline phosphatase (ALP), alanine aminotransferase\r\n(ALT), aspartate aminotransferase (AST), and total bilirubin\r\nwere significantly (p < 0.05) reduced after treatment of\r\nrats with the formulation which were previously elevated\r\n(p < 0.05) in the CCl4-treated group when compared with the\r\nuntreated group. The CCl4-treated group exhibited significantly\r\ndifferent activities in liver SOD and GSH enzymes. The level of\r\nMDAwas lowered in the liver tissue samples of treated ratswhen\r\ncompared with the CCl4-exposed untreated rats. The groups\r\ntreated with the formulation showed signs of protection against\r\nthis toxicant as evidenced by the absence of necrosis. Hepacare®\r\nshowed reversal effects on the previously increased haematological\r\nparameters and damaged liver tissues with a potential to\r\nameliorate oxidative stress in hepatic dysfunction"^^ . "2017" . . . "Springer"^^ . . . "ORIGINAL ARTICLE"^^ . . . . . . . . . . . . . . . . . "O."^^ . "Okubena"^^ . "O. Okubena"^^ . . "H. A."^^ . "Adebayo"^^ . "H. A. Adebayo"^^ . . "Oluwatobi Samuel"^^ . "Adegbite"^^ . "Oluwatobi Samuel Adegbite"^^ . . "Omolara Faith"^^ . "Yakubu"^^ . "Omolara Faith Yakubu"^^ . . . . . . "Haematopoietic induction and hepatic protective roles\r\nof Hepacare® in CCl4-induced hepatic damaged rats (PDF)"^^ . . . "1.pdf"^^ . . . "Haematopoietic induction and hepatic protective roles\r\nof Hepacare® in CCl4-induced hepatic damaged rats (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #8971 \n\nHaematopoietic induction and hepatic protective roles \nof Hepacare® in CCl4-induced hepatic damaged rats\n\n" . "text/html" . . . "QH301 Biology"@en . . . . . . . . . . . . . . . "O."^^ . "Okubena"^^ . "O. Okubena"^^ . ""^^ . . "Oluwatobi Samuel"^^ . "Adegbite"^^ . "Oluwatobi Samuel Adegbite"^^ . ""^^ . . "H. A."^^ . "Adebayo"^^ . "H. A. Adebayo"^^ . ""^^ . . "Omolara Faith"^^ . "Yakubu"^^ . "Omolara Faith Yakubu"^^ . ""^^ .