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Antimicrobial Activity and Micro-Flora Quality Evaluation of Commonly Used Toothpastes

Oranusi, S. U. and Akhigbe, Edi (2013) Antimicrobial Activity and Micro-Flora Quality Evaluation of Commonly Used Toothpastes. International Journal of Biology,Pharmacy and Allied Sciences, 2 (7). pp. 1388-1399. ISSN 2277–4998

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To determine the microbiological quality and antimicrobial activity and effectiveness of commonly used toothpaste, thirty products consisting of eight brands of toothpaste were evaluated using standard methods and Staphylococcus aureus and Candida albicans as test organisms. All the toothpastes were sterile, and had some levels of antimicrobial activity at neat and 10-1 dilutions. Colgate and Signal had the highest zones of inhibition 20mm and 12mm against Staphylococcus aureus. Colgate and Macleans herbal neat concentration had the highest inhibition of 11mm and 10mm on Candida albicans. Colgate and Macleans had a minimum inhibitory concentration greater than 10-3 for Staphylococcus aureus. The other toothpastes showed minimum inhibitory concentration of 10-1 and 10-2. Close Up herbal and Colgate had minimum inhibitory concentrations of greater than 10-3 for Candida albicans. At 10-2 dilution, total bacteria count of colonies increased as the time of exposure increased for most of the toothpastes. There was however, a general decline in the number of Candida colonies as the time of exposure increased. The toothpastes reduced and inhibited the test organisms mainly as neat and at 5 and 10 minutes. It is advocated that brushing the teeth for 5 to 10 minutes will allow for enough contact time for toothpaste to act on oral microbes and importantly pathogens for maximum result of good oral hygiene. Further studies on the relationship of brushing mannerism and toothpaste use culture are necessary. Regular survey of personal care products at the consumer level is advised to help keep the consumers informed of quality of products and checkmate producers of fake product and thus help stamp out unwholesome product from our markets

Item Type: Article
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Mr Solomon Bayoko
Date Deposited: 05 Dec 2013 09:56
Last Modified: 05 Dec 2013 09:56

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