Ajani, Olayinka O. and Obafemi, C. A. and Ikpo, C. O. and Ogunniran, K. O. and Nwinyi, Obinna (2009) Microwave-Assisted Synthesis and Antibacterial Activity of some Pyrazol-I-Ylquinoxalin-2(IH)-One Derivatives. ХИМИЯ ГЕТЕРОЦИКЛИЧЕСКИХ СОЕДИНЕНИЙ (11). pp. 1703-1713.
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Abstract
3-Hydrazinoquinoxalin-2(1H)-one was prepared from quinoxaline-2,3-dione and subsequently used for the synthesis of some potentially biologically active 3-(pyrazol-1-ylquinoxalin-2(1H)-one derivatives. While 3-(3,5-dimethylpyrazol-1-yl)quinoxalin-2(1H)-one showed a comparative effect with streptomycin, 3-(5-oxo-3-phenyl-4,5-di- hydropyrazol-1-yl)quinoxalin-2(1H)-one was found to be the most active at MIC value of 7.8 μg/ml
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 3-hydrazinoquinoxalin-2(1H)-one, imines, gram-positive bacteria |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology Q Science > QR Microbiology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Biological Sciences |
| Depositing User: | Mr Solomon Bayoko |
| Date Deposited: | 19 Jan 2015 10:27 |
| Last Modified: | 19 Jan 2015 10:38 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/3356 |
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