Oxyphyllones A and B, novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla

Xu, Jun-Ju and Tan, Ning-Hua and Xiong, Jiang and Adebayo, H. A. and Han, Hong Jin and Zeng, Guang-Zhi and JI, Chang-Jiu and Zhang, Yu-Mei and Zhu, Mei Ju (2009) Oxyphyllones A and B, novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla. Chinese Chemical Letters , 2009 (20). pp. 945-948. ISSN 1001-8417

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Abstract

Two novel 4,5-secoeudesmane sesquiterpenoids, oxyphyllones A (1) and B (2) were isolated from the fruits of Alpinia oxyphylla. Their structures were established by spectroscopic methods including 1D and 2D NMR spectra. These two compounds are the first example of naturally occurring sesquiterpenoids with a 4,5-secoeudesmane skeleton in the family of Zingiberaceae and oxyphyllone A (1) is the first 4,5-secoeudesmane type of 13-norsesquiterpenoid. Compounds 1 and 2 exhibited no cytotoxicities against three cancer cell lines at 10 mg/mL.

Item Type:	Article
Uncontrolled Keywords:	Alpinia oxyphylla; Zingiberaceae; 4,5-Secoeudesmane sesquiterpenoid; Oxyphyllone A; Oxyphyllone B
Subjects:	Q Science > Q Science (General) Q Science > QR Microbiology
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mrs Aderonke Olufunke Asaolu
Date Deposited:	07 Mar 2016 11:20
Last Modified:	07 Mar 2016 11:20
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/6385

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