Efficiency of Pleurotus florida dietary supplement in reducing Cadmium toxicity in Albino Rat (Rattus norvegicus)

Ekaye, S. O. and Erhunmwunse, N. O. and Ejoh, Akpoyovware S. (2017) Efficiency of Pleurotus florida dietary supplement in reducing Cadmium toxicity in Albino Rat (Rattus norvegicus). NIGERIAN ANNALS OF NATURAL SCIENCES, 15 (1). 038-042. ISSN 1115-2702

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Abstract

Pleurotus florida was investigated to reduce cadmium toxicity via haematological and histopathological analysis in Wistar albino rats. A total number of 28 Rattus norvegicus were divided into 7 groups (2 male and 2 female) different feeding concentration of cadmium and mushroom. Clinical signs observed during the 16days dosing period include loss of appetite, weight loss, diarrhoea, sluggishness and coughing, for the treated groups (B -G). Haematology results showed that there were significant differences (p<0.05) in WBC, PLT, MCH and MCHC but they were no significant differences (p>0.05) in RBC, MCV, MPV, LY and Hgb of the treated groups. The histopathological alterations in sleep were time and sex dependent ranging from slightly atrophied follicle to moderate atrophied follicle in both male and female rat, but more severe in female. Abatement of Cadmium toxicity from this experiment using P. florida was successful although was dependent on the concentration of the exposed metal.

Item Type:	Article
Uncontrolled Keywords:	Pleurotus florida, Rattus norvegicus, Cadmium toxicity, Histopathology.
Subjects:	Q Science > Q Science (General) Q Science > QH Natural history Q Science > QH Natural history > QH301 Biology
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mrs Patricia Nwokealisi
Date Deposited:	12 Sep 2018 11:58
Last Modified:	12 Sep 2018 11:58
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/11553

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