Ajani, Olayinka O. and ltuen, Ruth ltoroabasi and Falomo, A. (2011) Facile Synthesis and Characterization of Substituted Pyrimidin-2(1.H)-ones and their Chalcone Precursors. Pak. j. sci. ind. res. Ser. A: phys. sci, 54 (2). pp. 59-67.
![[img]](http://eprints.covenantuniversity.edu.ng/style/images/fileicons/other.png) |
PDF
Download (908Kb) |
Abstract
A new and efficient method has been developed for the quantitative transformation of chalcon.es to pyrimidine frame work via solid support catalysis. Silica supported sulphuric acid (SSA) efficiently catalyzed the reaction of a-[3-unsaturated carbonyl, chalcones (1-10) with urea to afford substituted pyrimidin-2(1H)-ones (11-20) in good to excellent yield. The interesting behaviour of SSA lies in the fact that it can be re-used after simple washing with chloroform thereby rendering this procedure more economical. The chemical structures were confrrmed by analytical data as well as spectroscopic means
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | catalyst, spectroscopic means, chalcones, 4-phenylbut-3-en-2-one |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Chemistry |
| Depositing User: | Mrs Hannah Akinwumi |
| Date Deposited: | 28 Mar 2019 08:26 |
| Last Modified: | 28 Mar 2019 08:26 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/12535 |
Actions (login required)
 |
View Item |
