Antimicrobial and GC-MS Analyses of Stem and Root Extracts of Bidens Pilosa Linn

Ajanaku , C. O. and Echeme, Johnbull O and Mordi, Raphael C. and Ajani, Olayinka O. and Okere, Daniel U. and Kayode, Abolanle A. (2019) Antimicrobial and GC-MS Analyses of Stem and Root Extracts of Bidens Pilosa Linn. Oriental Journal of Chemistry, 35 (2). ISSN 0970-020 X

PDF Download (248Kb)

Abstract

This study describes the qualitative phytochemical screening, antimicrobial and GC-MS analyses of the crude methanol extract of the stem and roots parts of Bidens pilosa partitioned between methanol, dichloromethane, ethyl acetate and hexane solvents. Phytochemical analysis indicated the presence of cardiac glycosides, terpenoids, flavonoids and alkaloids. Saponins were not found in any of the fractions of stem and root of B. pilosa. Antibacterial studies indicated that the lowest concentration (6.25 mg/mL) was achieved for Candida subtilis for the ethyl acetate fraction of the stem extract and hexane fraction of the root extract. Antimycobacterial test activity of these solvent fractions revealed that the hexane fraction of the root extract was susceptible to the bacterium isolate. Gas chromatography-Mass spectrometric study revealed the presence of the following compounds-cis-9-Hexadecenal, 2-hydroxyl ethyl (Z)-9-Octadecenoate, Octadecanal, Oleic acid, 4-(dimethylamino)-Benzaldehyde, 4,6,7-Trimethoxy-2,3-dihydrofuro(2,3-b)quinolone

Item Type:	Article
Uncontrolled Keywords:	Bidens pilosa, Antibacterial studies, Medicinal plants, Phytochemicals, Antimicrobial, Anti-mycobacterial, Gas chromatography-mass spectrometry
Subjects:	Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Engineering, Science and Mathematics > School of Chemistry Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mrs Patricia Nwokealisi
Date Deposited:	08 Apr 2019 15:00
Last Modified:	08 Apr 2019 15:00
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/12581

Actions (login required)

View Item