AGBEYANGI, OLUBISOLA ARIKE and Covenant University, Theses (2017) THE EFFECT OF ABO BLOOD GROUP CLASSIFCATIONS ON BIOCHEMICAL AND ANTIOXIDANT MARKERS OF HEALTHY ADULTS. Masters thesis, COVENANT UNIVERSITY.
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Abstract
This research work was aimed at assessing the consequence of ABO blood types on biochemical and antioxidant markers in healthy adult. A total of seventy (n=70) adult of both sexes were recruited into the study. All participants were assumed healthy provided they have not been on medication for a period of two weeks prior to their recruitment. Antioxidant markers assessed includes superoxide dismutase (SOD), glutathione-Stransferase (GST), reduced glutathione (GSH), lipid peroxidation while biochemical markers assessed includes albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, urea, uric acid, cholesterol, triglyceride and lowdensity lipoprotein (LDL). Blood group O has the highest frequency of 42 %, while AB has the lowest frequency of 12.9 %. A significant positive correlation was seen between weight and BMI, also a negative correlation was seen between total cholesterol and BMI. The activity of GST and GSH increased significantly (p< 0.05) among the blood types for the antioxidant assay in the blood type A, also results of the liver function test reveals that the activity of AST and albumin decreased significantly for the liver function test among the blood types (p< 0.05) in blood types A. For the kidney function test, the activity of creatinine increased significantly (p< 0.05) while urea reduced significantly (p< 0.05) in both blood group A and O. The level of blood total cholesterol increased significantly (p< 0.05) in blood group B; but decreased significantly (p< 0.05) in blood group A and AB for the lipid profile assayed. The effects of the ABO groups were more pronounced on the antioxidant activity of GST and SOD, and other biochemical parameters such as Total cholesterol, LDL, creatinine, and urea; these may be indicator
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Chemistry |
| Depositing User: | Mrs Hannah Akinwumi |
| Date Deposited: | 23 Mar 2020 10:24 |
| Last Modified: | 23 Mar 2020 10:24 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/13236 |
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