Iweala, E. E. J. and Obidoa, O. (2009) Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats. Pakistan Journal of Nutrition, 8 (8). pp. 1199-1203. ISSN 1680-5194
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Abstract
Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation, haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-stransferase and Superoxide dismutase. Histological changes associated with Telfairia occidentalissupplemented diet on the liver, intestine and testes were also examined. Results showed that Telfairia occidentalis-supplemented diet caused a significant increase (p<0.05) in weight and haemoglobin. Cholesterol and lipid peroxidation were significantly reduced (p<0.05). There were however no significant changes in the enzymes including Aspartate minotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-s-transferase and Superoxide dismutase. Only Alkaline phosphatase was significantly reduced (p<0.05). Histological changes showed hypertrophy of the intestinal propia and reduced globlet cells while the testes exhibited thick basement membrane and large spermatogonia.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Telfairia occidentalis, weight, haemoglobin, cholesterol, lipid peroxidation |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Biological Sciences |
| Depositing User: | Mr Adewole Adewumi |
| Date Deposited: | 23 Jun 2011 18:41 |
| Last Modified: | 13 Dec 2011 21:13 |
| URI: | http://eprints.covenantuniversity.edu.ng/id/eprint/257 |
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