Phytochemical and Antimicrobial Activities of the Leaf Oil Extract of Mentha Spicata and its Efficacy in Repelling Mosquito

Ojewumi, M. E. and Adedokun, Samuel Oluwafunsho and Omodara, O. J. and Oyeniyi, Esther Adenike and Taiwo, O. S. and Ojewumi, E.O. (2017) Phytochemical and Antimicrobial Activities of the Leaf Oil Extract of Mentha Spicata and its Efficacy in Repelling Mosquito. International Journal of Pharmaceutical Research & Allied Sciences, 6 (4). pp. 17-27. ISSN 2277-3657

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Abstract

Synthetic drugs and repellents have been discovered to have adverse toxicity effects apart from the fact that they are no longer efficient due to adaptation of microbes and mosquitoes to them. This study is based on using the extract from local leaves (Mentha spicata plant) as treatment for microbial diseases as well as mosquito repellent. Extract of leaf were studied and screened for the presence of phytochemicals (secondary metabolites) and antimicrobial properties against some fungi and bacteria viz., Pseudomonas aeruginosa, Bacillus Subtilis, Staphylococcus aureus, Aspergillus niger, Escherichia coli and Saccharomyces cerevisiae. The result of the phytochemical screening revealed that the leave extract contained tannin, steroids, flavonoids, terpenoids, phenols and cardiac glycosides while anthraquinones and saponins were not determined. From the microbial analysis the zone of inhibitions indicated that the extract of Mentha spicata plant had strong activity against bacteria and fungi used in this analysis. Mentha spicata oil extract with the highest concentration when introduced into the produced cream had the highest repellency time lasting up to four [4] hours. The chemical constituents of the leaf oil extract were analyzed using Gas chromatography- mass spectroscopy (GC-MS) and the major chemical constituent identified was carvone

Item Type:	Article
Uncontrolled Keywords:	Mentha spicata; Phytochemical; Antimicrobial; Oil Extract; Efficacy
Subjects:	T Technology > T Technology (General) T Technology > TP Chemical technology
Divisions:	Faculty of Engineering, Science and Mathematics > School of Engineering Sciences Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mrs Patricia Nwokealisi
Date Deposited:	11 Jan 2018 08:35
Last Modified:	11 Jan 2018 08:35
URI:	http://eprints.covenantuniversity.edu.ng/id/eprint/9966

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